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Course Contents

GENERAL MICROBIOLOGY: Historical Introduction, Scope of Microbiology with special reference to Pharmaceutical Sciences. Nomenclature and classification of Micro-organisms. MICRO-ORGANISMS: a) The Bacteria: General and cellular Morphology, structure and function. Classification of Bacteria. Growth curve, growth factors and growth characteristics. Nutrition Requirements and Nutrition factors affecting growth. Culture Media, Bacterial cultures and staining methods. b) The Viruses: Introduction, Classification (and detail of at least one species from every group), cultivation and replication.c) The Fungi/Yeast/Molds: d) The Protozoa: THE NORMAL FLORA: (a) Microbiology of air, water and soil (general introduction and normal inhibitants of air, water and soil). (b) Normal flora of Skin, Intestinal tract, Ear, Nose etc. INDUSTRIAL MICROBIOLOGY: Introduction to Sterilization/Disinfection. Fermentation. Pharmaceutical products produced by fermentation process (Penicillins, Cephalosporins, Gentamycin, Erythromycin, Tetracyclines, Rifamycin, Griseofulvin). IMMUNOLOGY: Introduction and types of Immunity: Specific and non-specific (Cellular basis of Immune response. Immunity, autoimmunity, tolerance. Antigen. Anti-bodies). Antigen-Antibody reactions and their clinical and diagnostic applications. Hypersensitivity and allergy. Drug allergy mechanism. Vaccination: Introduction and aims. Types of Vaccines. Current vaccine practices. FACTORY & HOSPITAL HYGIENE including GOOD MANUFACTURING PRACTICES: Introduction, Control of Microbial contamination during manufacture. Mnaufacture of Sterile products, A Guide to Current Good Pharmaceutical Manufacturing Practices. INTRODUCTION TO DISEASES: Dengue fever, Bird flu, SARS, or other prevailing diseases of bacteria and virus

Course Synopsis

To comprehend the students with the classification, characterization, metabolism and genetic information of microorganisms. Explain the concepts of sterilization, disinfection and antibiotics production. Overall develop the understanding of importance of microbiological principles and its importance in pharmaceutical industry and products.

Course Learning Outcomes

To develop an understanding of microbiological principles in pharmaceutical industry and products and an understanding of immunological prevention against various viral and bacterial diseases..

Practical description for Culture sensitivity Test/ Kirby Bauer test

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Practical description For Gram Staining

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Practical description for streak plate method

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Book Title : Jawetz, Melnick & Adelberg's Medical Microbiology and Immunology
Author : Brooks G, Carroll KC, Butel J, Morse S, Mietzner T.
Edition : 27 edition (November 20, 2015)
Publisher : McGraw-Hill Education / Medical

Book Title : Hugo and Russell's Pharmaceutical Microbiology
Author : Hugo WB, Russell AD
Edition : 8 edition (August 22, 2011)
Publisher : Wiley-Blackwell

Title : Sterilization
Type : Presentation

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Title : Disinfectants
Type : Other

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Title : The virus
Type : Presentation

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