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Course Contents

Asymmetric synthesis in Organic Chemistry: Reactions involving C-C single bond: Generation of Enolate and enamine, enolates, stability and thermodynamic control during generation of carbanions, thermodynamically and kinetically controlled products, competition between C and O- alkylation; reactions and stereochemistry of enolates: asymmetric synthesis involving chemoselective and regioselective oxidation–reduction reactions.

Course Synopsis

this course include the Asymmetric synthesis and role of asymmetric synthesis in drugs and medicine.chiral pool, chiral auxillary and chiral regent and catalyst play an important role in asymmetric synthesis. Asymmetric synthesis involves almost in all types of reactions. some basic concept of stereochemistry and specific terms regarding chiral synthesis is also included in this course

Course Learning Outcomes

To learn what is stereochemistry, how stereochemistry effects the on nature of compounds, how importance to achieve target sterochemistry of compound for an specific drugs. to understand what are the methods which is used to achieve asymmetric synthesis.

Asymmetric synthesis

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importance of Asymmetric synthesis

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Asymmetric methods

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principle of asymmetric synthesis

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Book Title : organic Chemistry chap 45
Author : Jonathan Clayden, Nick Greeves, and Stuart Warren
Edition : 1st
Publisher : Oxford university press

Book Title : stereochemistry of organic compound
Author : Ernest Ludwig Eliel, Samuel H. Wilen, Lewis N. Mander
Edition : 2nd
Publisher :

Title : Asymmetric synthesis
Type : Other

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Title : catalytic asymmetric synthesis
Type : Other

View catalytic asymmetric synthesis

Title : chirality and Asymmetric synthesis
Type : Other

View chirality and Asymmetric synthesis