Lecture 1: Introduction to metabolism and basic aspects of bioenergetics and biochemical thermodynamics (endergonic and exergonic reactions); phosphoryl group transfer and ATP production; metabolism, oxidation-reduction;
Lecture 2: carbohydrate metabolism and regulation (glycolysis, glycogenolysis; gluconeogenesis; pentose phosphate pathway);
Lecture 3: citric acid cycle (reactions, energetics and control),
Lecture 4: electron transport chain, oxidative phosphorylation, shuttle mechanisms (glycerol-phosphate shunt),
Lecture 5: lipid metabolism (energy yield from fatty acid oxidation.ketone bodies, acyl glycerol, compound lipids, cholesterol);
Lecture 6: photosynthesis;
Lecture 7: Calvin Cycle;
Lecture 8: metabolism of nitrogenous compounds (amino acid catabolism, urea cycle
Lecture 9: amino acids, purine and pyrimidine synthesis); nucleic acid metabolism and control; integration of metabolism.
This course is a continuation of Principles of Biochemistry I, and aims to familiarize students with the key concepts of intermediary metabolism of proteins, nucleic acids, carbohydrates and lipids.
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