Course Contents

Lecture 1: Introduction to metabolism and basic aspects of bioenergetics and biochemical thermodynamics (endergonic and exergonic reactions); phosphoryl group transfer and ATP production; metabolism, oxidation-reduction; Lecture 2: carbohydrate metabolism and regulation (glycolysis, glycogenolysis; gluconeogenesis; pentose phosphate pathway); Lecture 3: citric acid cycle (reactions, energetics and control), Lecture 4: electron transport chain, oxidative phosphorylation, shuttle mechanisms (glycerol-phosphate shunt), Lecture 5: lipid metabolism (energy yield from fatty acid oxidation.ketone bodies, acyl glycerol, compound lipids, cholesterol); Lecture 6: photosynthesis; Lecture 7: Calvin Cycle; Lecture 8: metabolism of nitrogenous compounds (amino acid catabolism, urea cycle Lecture 9: amino acids, purine and pyrimidine synthesis); nucleic acid metabolism and control; integration of metabolism.

Course Synopsis

This course is a continuation of Principles of Biochemistry I, and aims to familiarize students with the key concepts of intermediary metabolism of proteins, nucleic acids, carbohydrates and lipids.