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Course Contents

Endocrine system: Mechanisms of action of hormones. Chemistry, Metabolism and Biological functions of Pancreateic, Pituitary, Gonadal, Adrenal, Thyroid, Parathyroid, Intestinal and Renal harmones. Pheromones. Hormonal control mechanisms. 2. Metabolism of Amino acids and Proteins: Digestion and Absorption of Proteins. Biosynthesis of essential amino acids. Degradation of amino acids, Urea Cycle Decarboxylation, transamination and deamination reactions of amino acids and their importance. Creatine and creatinine synthesis and secretion. 3. Metabolism of Nucleic Acids: Biosynthesis and Catabolism of Purines and Pyrimidines. Biosynthesis of nucleotides. Disorders linked to serum urate levels. Synthesis of RNA and splicing.

Course Synopsis

This course is aimed to deliver comprehensive knowledge regarding the form and function of endocrine glands with special emphasis on the chemistry and mechanism of action of the hormones and pheromones of human body. The course also emphasizes on comprehension of biosynthesis, degradation and diseases related to nucleic acids along with a detailed knowledge on the metabolic, assimilatory processes and diseases related to amino acids and proteins in the human body.

Course Learning Outcomes

The students of this course will be able to learn the elements appended below. 1. Understanding the human endocrinology, chemical background, biosynthesis, specificity, mechanisms of action and feedback inhibition regarding the stimulation, release and effect of hormones and pheromones. 2. Biosynthesis and degradation of purine and pyrimidine bases and phenomena leading to assembly of DNA and RNA respectively. 3. Metabolism and assimilation of proteins in the body for a chemist to be able to identify, experiment and resolve the problems and diseases related to them.

Gout & Hyperuricemia

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RNA splicing

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enzyme kinetics

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Enzyme inhibitiors

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Regulatory enzyme and mechanism of enzyms

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Disorders linked to serum urate levels

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Synthesis of RNA and splicing

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Book Title : Biochemistry
Author : Jeremy M Berg, John L Tymoczko, and Lubert Stryer.
Edition : 5th edition
Publisher : New York: W H Freeman; 2002.
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Title : Nucleotide synthesis
Type : Presentation

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