Course Contents

The mass spectrometer, ionization and ion source, mass analyzers, metastable ion, ion detection, and recording. Electron impact and chemical ionization, field ionization, field desorption, fast atom bombardment, plasma desorption, thermospray, electrospray mass spectra. Fragmentation pattern of common functional groups. Structure elucidation using mass spectrometry in conjunction with other spectroscopic techniques.

Course Synopsis

To learn the principle of operation of a mass spectrometer • To be able to interpret the mass spectra of atoms and small molecules containing isotopes • To learn how mass spectrometry can be applied to interpret the different functional groups • Interpret and correlate the information provided by the various types of mass spectra.

Course Learning Outcomes

At the end of this course, students should be able to: Explain the principles of mass spectrometry, Describe the different mass spectrometers available, Compare the data acquisition capabilities of the different instruments and Interpret the spectra of different functional groups Interpret and evaluate the information contained in the several types of spectra obtained with different types of mass spectrometers. Design an adequate experiment to solve a problem using mass spectrometry. Analyze the validation of the results obtained in the resolution of a problem by mass spectrometry.