Course Contents

PRINCIPLES OF PHARMACEUTICAL FORMULATION AND DOSAGE FORM DESIGN: Need for dosage form; Preformulation Studies; Product Formulation. ADVANCED GRANULATION TECHNOLOGY (DESIGN & PRACTICE): Spray Drying Granulation Technology; Roller Compaction Technology; Extrusion/Spheronization as a Granulation Technique; Single Pot Processing. Granulation Technology: Rapid Release Granulation Technique; Particle Coating by Centrifugation Granulation Technology. POLYMERS USED IN DRUG DELIVERY SYSTEMS: NOVEL DRUG DELIVERY SYSTEM (DDS): Sustained/ Controlled Release Drug Delivery System Microencapsulation technique, Coacervation, Solvent evaporation, Interfacial polymerization, Spray drying Developmental aspects of Matrix and Reservoir Systems. NOVEL GIT DRUG DELIVERY SYSTEM: a. Oral Osmotic Pumps b. Ion-Exchange Controlled DDS c. pH-Controlled DDS d. Bio/mucoadhesive DDS e. Floating DDS DRUG CARRIER SYSTEM: a. Liposomes b. Niosomes TARGETED DRUG DELIVERY SYSTEM: a. Active Drug Delivery System b. Passive Drug Delivery System PHARMACEUTICAL BIOTECHNOLOGY: a. Introduction to Biotechnology: Genetics/Genomics, Proteomics, Biomolecular target Identification, Pharmacogenomics, Gene therapy and Nucleic acid therapeutics. b. Techniques Used in Pharmaceutical biotechnology: PCR, DNA Sequencing, Affinity Protein Purification. c. Fundamentals of Genetic Engineering and its Application in Medicine. d. Pharmaceutical Recombinant therapeutic Proteins, Growth factors, Therapeutic antibodies, High-throughput screening of putative therapeutic compounds. e. Biotechnological aspects in the product development. f. Principle, Synthesis and Application of Monoclonal Antibodies. g. Immobilized Enzymes and their application in Medicine.

Course Synopsis

To empower the students with the concepts of novel drug delivery and development. Details about formulation and evaluation of novel drug delivery mechanisms is integral part of pharmaceutical technology. Discuss the Importance and utilization of biotechnological principles in modern therapeutics and targeted drug delivery.

Course Learning Outcomes

To empower the students with the concepts of novel drug delivery and development. Details about formulation and evaluation of novel drug delivery mechanisms is integral part of pharmaceutical technology. Discuss the Importance and utilization of biotechnological principles in modern therapeutics and targeted drug delivery. .