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Course Contents

Physiological chemistry Respiration: Structure and function of lungs, Physical exchange of gases, Transport of oxygen by blood, Transport of CO2 in blood, Bu(er system of the blood, Acid-Base balance. Kidney: Structure and function of nephrons, Formation of urine, Filtration, Glomerular 8ltration rate, Action of the tubule, Reabsorption of Na, Cl and water, Loop of Henle. Structure and function of muscle tissues, Nerve tissues and Connective tissues, Nerve conduction and sensory system. Circulatory system. Chemotherapy: Antibiotics, their mode of action, the mechanism of resistance bacteria show against them Structure and mode of action of antipyretics analgesic, antimalarial, sulpha-drugs, antibiotics with special reference to pencillin, sulphanilamides. Mechanism of drugs action and resistance. Drug metabolism and biotransformation, Chemotherapy and cancer.

Course Synopsis

This course covers physiology, biochemistry and pathology of different body organs (Lungs, kidneys , nerv e and muscle tissues). The second part of the course covers the Antibiotics, their mode of action, the mechanism of resistance bacteria show against them, Structure and mode of action of different groups of Antibiotics, Drug metabolism and biotransformation, Chemotherapy and cancer.

Course Learning Outcomes

After completing this course the students will understand the physiology, biochemistry and pathology of different body organs. They will have a detailed knowledge about Antibiotics, their mode of action, the mechanism of resistance bacteria show against them,Drug metabolism and biotransformation, Chemotherapy and cancer.


Drug metabolism

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phase 1 reactions

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phase 2 reactions

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Book Title : Text Book of Medical Physiology
Author : Guyton, C and Hall J. C
Edition : 2016
Publisher : Elsevier
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Book Title : The Text Book of Biochemistry with Clinical Correlation
Author : Devlin, T. M
Edition : 1997
Publisher : Wiley- Liss, New York .







Title : Antibiotic resistance mechanism
Type : Other

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Title : Pharmacokinetics vs pharmacodynamics
Type : Presentation

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