Course Contents

Introduction to metabolism and basic aspects of bioenergetics and biochemical thermodynamics (endergonic and exergonic reactions); phosphoryl group transfer and ATP production; metabolism, oxidation-reduction; carbohydrate metabolism and regulation (glycolysis, glycogenolysis; gluconeogenesis; pentose phosphate pathway); metabolism of glycogen; citric acid cycle (reactions, energetics and control), electron transport chain, oxidative phosphorylation, shuttle mechanisms (glycerol-phosphate shunt), lipid metabolism (energy yield from fatty acid oxidation, oxidation of unsaturated and poly unsaturated fatty acids, ketone bodies, acyl glycerol, compound lipids, cholesterol); photosynthesis; Calvin Cycle; metabolism of nitrogenous compounds (amino acid synthesis, catabolism, purine and pyrimidine synthesis); nucleic acid metabolism and control; urea cycle; integration of metabolism.

Course Synopsis

This course is a continuation of Principles of Biochemistry I, and aims to familiarize students with the key concepts of intermediary metabolism of proteins, nucleic acids, carbohydrates and lipids.